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Intravenous gammaglobulin-associated acute renal failure

โœ Scribed by N. Gupta; I. Ahmed; S. Nissel-Horowitz; D. Patel; B. Mehrotra


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
14 KB
Volume
66
Category
Article
ISSN
0361-8609

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โœฆ Synopsis


Intravenous gammaglobulins are used for the treatment of various auto-immune hematological disorders. Renal failure is a relatively rare, but an increasingly recognized side effect of gammaglobulin therapy. Although the renal failure is usually reversible, renal replacement therapy is required occasionally. A high index of suspicion, early recognition and appropriate intervention can prevent this complication. We herewith describe two patients with an immune hematological disorder, who developed acute renal failure after treatment with intravenous gammaglobulins. A brief review of the possible risk factors, pathophysiology and management of this complication is provided. Am. J. Hematol. 66:151-152, 2001.


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