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Intrauterine infection with human parvovirus B19: A light and electron microscopy study

✍ Scribed by Dr. E. Owen Caul; M. Jane Usher; Patricia A. Burton

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
799 KB
Volume
24
Category
Article
ISSN
0146-6615

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✦ Synopsis

Recent reports have documented human parvovirus B19 infection in pregnancy, which may lead to spontaneous abortion, stillbirth or hydrops fetalis. Transplacental infection in a case of hydrops fetalis is demonstrated by light and electron microscopy observation of virus inclusions in all tissues examined. Parvovirus particles measuring approximately 20 nm were observed within the nuclei of erythropoietic cells. The parvovirus virions were observed most commonly as randomly distributed particles and rarely in crystalline assays. Thus definitive evidence of fetal infection confined to red cell precursors is documented.

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