Recent reports have documented human parvovirus B19 infection in pregnancy, which may lead to spontaneous abortion, stillbirth or hydrops fetalis. Transplacental infection in a case of hydrops fetalis is demonstrated by light and electron microscopy observation of virus inclusions in all tissues exa
Angio-oedema in a neonate with IgG antibodies to parvovirus B19 following intrauterine parvovirus B19 infection
β Scribed by S. Miyagawa; Y. Takahashi; A. Nagai; Y. Yamamoto; A. Nakagawa; K. Hori; H. Morikawa; A. Yoshioka; T. Shirai
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 268 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0007-0963
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β¦ Synopsis
We report a neonate with angio-oedema following fetal hydrops caused by maternal parvovirus B19 infection. Levels of complement components, including total haemolytic complement activity and C1 inhibitor concentration, were within normal ranges in cord blood. Neonatal angio-oedema might be included in the clinical spectrum of parvovirus B19 infection in pregnancy.
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## Abstract ## Objective To show a possible association between parvovirus B19 infection and the presence of antiphospholipid antibodies (aPL) in patients with rheumatic diseases. ## Methods Serum samples obtained from 88 children with various forms of juvenile rheumatic disease and from 40 adul