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Case report: Electron microscopic detection of human parvovirus (B19) in a patient with HIV infection

✍ Scribed by Dr. Ian L. Chrystie; June D. Almeida; Jan Welch

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 741 KB
Volume: 30
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890300404

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We report the findings on an HIV‐positive patient found to be infected with human parvovirus B19. In a comparative study of sequential sera, direct electron microscopy (EM) had the same sensitivity as DNA hydridisation for the detection of the virus. EM did not require specific reagents and also yielded information on the state of the virus; i.e., whether random or complexed, and the type of antibody involved. The presence of parvovirus complicated the judgement as to drug treatment. This case also highlighted the importance of diagnosing the presence of opportunistic viral infections that have no, or lowgrade, pathogenic activity.

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