✦ LIBER ✦

Detection of parvovirus B19 in a skin biopsy of a patient with erythema infectiosum

✍ Scribed by Dr. Tino F. Schwarz; Siegfried Wiersbitzky; Manfred Pambor

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 509 KB
Volume: 43
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890430214

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We report the findings on a skin biopsy taken from a child acutely infected with parvovirus B 19 showing the typical exanthematous rash. By indirect immunofluorescence with a monoclonal antibody to B19, viral capsid proteins were detected in epidermal cells localized mainly in the stratum basale. Additionally, B 19 DNA was detected in epidermal cells of the stratum basale by in situ hydridization using a Dig‐labelled B19 DNA probe. The detection of viral capsid proteins and viral DNA suggests the presence of complete viral particles. It is therefore concluded that B19 plays a direct role in the formation of the exanthematous rash in erythema infection. © 1994 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Case report: Electron microscopic detect

Case report: Electron microscopic detection of human parvovirus (B19) in a patient with HIV infection

✍ Dr. Ian L. Chrystie; June D. Almeida; Jan Welch 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 741 KB

## Abstract We report the findings on an HIV‐positive patient found to be infected with human parvovirus B19. In a comparative study of sequential sera, direct electron microscopy (EM) had the same sensitivity as DNA hydridisation for the detection of the virus. EM did not require specific reagents

Frequent infection with a viral pathogen

Frequent infection with a viral pathogen, parvovirus B19, in rheumatic diseases of childhood

✍ Hartwig W. Lehmann; Antje Knöll; Rolf-Michael Küster; Susanne Modrow 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 80 KB 👁 1 views

Persistence of parvovirus B19 DNA in syn

Persistence of parvovirus B19 DNA in synovium of patients with haemophilic arthritis

✍ K. Zakrzewska; A. Azzi; E. De Biasi; P. Radossi; R. De Santis; P.G. Davoli; G. T 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 91 KB

## Abstract A progressive arthropathy develops commonly in haemophiliacs and its pathogenesis is not fully understood. Human parvovirus B19 has been associated with several diseases including acute and chronic arthropathy and some studies suggest its implication in chronic inflammatory diseases of

Detection of parvovirus B19 DNA by polym

Detection of parvovirus B19 DNA by polymerase chain reaction in giant cell arteritis: A case–control study

✍ Carlo Salvarani; Enrico Farnetti; Bruno Casali; Davide Nicoli; Liu Wenlan; GianL 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 65 KB 👁 1 views

Successful treatment of persistent eryth

Successful treatment of persistent erythroid aplasia caused by parvovirus B19 infection in a patient with common variable immunodeficiency with low-dose immunoglobulin

✍ Chuhjo, Tatsuya; Nakao, Shinji; Matsuda, Tamotsu 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 38 KB 👁 2 views

Parvovirus B19 causes persistent erythroid aplasia in immunocompromised hosts. From April through July 1996, we encountered five adult patients presenting with reticulocytopenia and fever caused by parvovirus B19 infection. The reticulocyte count of four patients with normal immunity recovered withi

Production of parvovirus B19 vaccine in

Production of parvovirus B19 vaccine in insect cells co-infected with double baculoviruses

✍ Eric I. Tsao; Michael R. Mason; Marco A. Cacciuttolo; Stephen H. Bowen; Gail Fol 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 997 KB

Recombinant human parvovirus B19 virus-like particles (VLPs), a candidate vaccine, were produced using the insect cell (Sf-9)-baculovirus (AcNPV) expression sys- tem. The synthesis and assembly of the particles in Sf-9 cells are directed by double infections with one recombinant virus (bacVP1) expre