Intramolecular Diels-Alder reactions of 1,2,4-triazines. Synthesis of 2,3-cyclopentenopyridines and 5,6,7,8-tetrahydroquinolines
โ Scribed by Taylor, Edward C.; Macor, John E.; French, Larry G.
- Book ID
- 120052874
- Publisher
- American Chemical Society
- Year
- 1991
- Tongue
- English
- Weight
- 867 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
Inverse electron-demand Diels-Alder reactions of 1,2,4-triazines, where the dienophile is present in a sidechain tethered to the azadiene, can proceed with remarkable facility, leading to a variety of condensed pyridines (Scheme 1). Several recent publications from our laboratory have served to illu
Syntheses of several 6,6,6-tricyclic condensed pyridines and pyrazines utilizing intramolecular Diels-Alder reactions of 1,2,4-triazines with alkyne and nitrile dienophiles are detailed. The cyclizations are facilitated by the presence 01 conformationally restrictive planar aromatic rings in the cha