Syntheses of several 6,6,6-tricyclic condensed pyridines and pyrazines utilizing intramolecular Diels-Alder reactions of 1,2,4-triazines with alkyne and nitrile dienophiles are detailed. The cyclizations are facilitated by the presence 01 conformationally restrictive planar aromatic rings in the cha
Intramolecular Diels-Alder reactions of 1,2,4-triazines. Routes to condensed pyrazines via cycloaddition of nitrile dienophiles
β Scribed by Taylor, Edward C.; French, Larry G.
- Book ID
- 120807586
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 719 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
Imidazole and 2-phenylimidazoleundergo intramolecularcycloadditions with 1,2,4triazines tethered betweenan imidazolenitrogenand the triazinylC3 position with a trimethylene chainto producetetrahydro-l,5-naphthyridines followingloss of N2 and a nitrile.
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