Syntheses of several 6,6,6-tricyclic condensed pyridines and pyrazines utilizing intramolecular Diels-Alder reactions of 1,2,4-triazines with alkyne and nitrile dienophiles are detailed. The cyclizations are facilitated by the presence 01 conformationally restrictive planar aromatic rings in the cha
Heterodienophilic intramolecular diels-alder reactions of 1,2,4 triazines. : Synthesis of novel polycyclic condensed pyrazines and lumazines
β Scribed by Edward C. Taylor; Joseph L. Pont; John C. Warner
- Book ID
- 108371811
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 711 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
Inverse electron-demand Diels-Alder reactions of 1,2,4-triazines, where the dienophile is present in a sidechain tethered to the azadiene, can proceed with remarkable facility, leading to a variety of condensed pyridines (Scheme 1). Several recent publications from our laboratory have served to illu
Diels-Alder Reactions of 1,2&Triazines. Synthesis of Novel Polycyclic Condensed Pyrazines and Lumaxines, Tetruhedron 43, 5159-5168 (1987). The following paragraph was inadvertently omitted from the above manuscript; it should appear at the end of page 5159 and before the beginning of the text on pag
Imidazole and 2-phenylimidazoleundergo intramolecularcycloadditions with 1,2,4triazines tethered betweenan imidazolenitrogenand the triazinylC3 position with a trimethylene chainto producetetrahydro-l,5-naphthyridines followingloss of N2 and a nitrile.
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