Intramolecular Diels-Alder Reaction of 8-Trifluoromethyl-1,3,8-Nona-Trienes: An Access to Angular Trifluoromethylated Hydrindenes
β Scribed by Gui-Dong Zhu; Bart Van Lancker; Dirk Van Haver; Pierre J. De Clercq
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 933 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0037-9646
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The synthesis of a novel series of 10-oxa-3-aza-tricyclo[5.2.1.0 1,5 ]dec-8-en-4-ones through the use of the intramolecular Diels-Alder reaction is presented. The use of this reaction allows for the synthesis of functionalized polycyclic systems in a stereocontrolled manner.
The title compound can be obtained with up to five asymmetric centres of known absolute configuration by a diastereoselective intramolecular Diels-Alder reaction between optically active N-substituted fuffurylamines and maleic anhydride, in which the chirality is transferred from one stereocentre to