Synthesis of a novel series of 10-oxa-3-aza-tricyclo[5.2.1.01,5]dec-8-en-4-ones through an intramolecular Diels–Alder reaction
✍ Scribed by Karen L. Milkiewicz; Irina B. Neagu; Daniel J. Parks; Tianbao Lu
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 126 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The synthesis of a novel series of 10-oxa-3-aza-tricyclo[5.2.1.0 1,5 ]dec-8-en-4-ones through the use of the intramolecular Diels-Alder reaction is presented. The use of this reaction allows for the synthesis of functionalized polycyclic systems in a stereocontrolled manner.
📜 SIMILAR VOLUMES
The title compound can be obtained with up to five asymmetric centres of known absolute configuration by a diastereoselective intramolecular Diels-Alder reaction between optically active N-substituted fuffurylamines and maleic anhydride, in which the chirality is transferred from one stereocentre to