Intracellular Mechanisms of Metabolism Regulation: The Role of Signaling via the Mammalian Target of Rapamycin Pathway and Other Routes
β Scribed by Vincenzo Flati; Evasio Pasini; Giuseppe D'Antona; Silvia Speca; Elena Toniato; Stefano Martinotti
- Book ID
- 113444780
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 509 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0002-9149
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Mammalian target of rapamycin (mTOR) is a protein serineβthreonine kinase that functions as a central element in signaling pathway involved in control of cell growth and proliferation. mTOR exists in at least two distinct multiβprotein complexes, mTORC1 and mTORC2. mTOR kinase controls
## Abstract Mammalian target of rapamycin (mTOR) mediates a signaling pathway that couples amino acid availability to S6 kinase (S6K) activation, translational initiation and cell growth rate, participating to a versatile checkpoint that inspects the energy status of the cell. The pathway is activa