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A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling

โœ Scribed by Jie Chen; Yimin Fang


Book ID
113993220
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
152 KB
Volume
64
Category
Article
ISSN
0006-2952

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Mammalian target of rapamycin: immunosup
โœ Robert T Abraham ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 555 KB

Recent findings have significantly advanced our understanding of the mechanism by which the potent immunosuppressive drug rapamycin inhibits cytokine-dependent lymphocyte proliferation. The protein targeted by the immunophilin-rapamycin complex is a member of a newly defined family of phosphoinositi