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Intracellular Ca2+, Force and Activation Heat in Rabbit Papillary Muscle: Effects of 2,3-Butanedione Monoxime

✍ Scribed by George Kotsanas; Sean M. Holroyd; Igor R. Wendt; Colin L. Gibbs

Book ID
115631860
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
455 KB
Volume
25
Category
Article
ISSN
0022-2828

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Effects of 2,3-butanedione monoxime on a
Effects of 2,3-butanedione monoxime on activation of contraction and crossbridge kinetics in intact and chemically skinned smooth muscle fibres from guinea pig taenia coli
✍ Γ…. Γ–sterman; A. Arner; U. Malmqvist πŸ“‚ Article πŸ“… 1993 πŸ› Springer Netherlands 🌐 English βš– 788 KB

The effects of 2,3-butanedione monoxime (BDM) were studied in smooth muscle fibres from guinea pig taenia colt. In intact muscle, active force during contractions induced by high-K + was inhibited by about 10% in I mM BDM and by approximately 70% in 10 mM BDM. Intracellular [Ca 2+ ] during contracti