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Intestinal Translocation Capabilities of Wheat Allergens Using the Caco-2 Cell Line

✍ Scribed by Bodinier, Marie; Legoux, Marie-Anne; Pineau, Florence; Triballeau, Sylvie; Segain, Jean-Pierre; Brossard, Chantal; Denery-Papini, Sandra


Book ID
127044636
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
224 KB
Volume
55
Category
Article
ISSN
0021-8561

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The transport of 10 amino acid ester prodrugs of levovirin (LVV) was investigated in the human intestinal Caco-2 cell line in order to overcome the poor oral bioavailability of LVV, an investigational drug for the treatment of hepatitis C infection. The prodrugs were designed to improve the permeabi