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Interspecies scaling: predicting clearance of drugs in humans. Three different approaches

โœ Scribed by Mahmood, I.; Balian, J. D.

Book ID
111889211
Publisher
Informa plc
Year
1996
Tongue
English
Weight
597 KB
Volume
26
Category
Article
ISSN
0049-8254

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๐Ÿ“œ SIMILAR VOLUMES

Interspecies scaling of protein drugs: P
Interspecies scaling of protein drugs: Prediction of clearance from animals to humans
โœ Iftekhar Mahmood ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 90 KB

The objective of this study was to evaluate the interspecies scaling for therapeutic protein drugs to predict the systemic clearance in humans from animal data. This study was undertaken to examine whether the rule of exponents of Mahmood and Balian for the prediction of clearance of nonprotein drug