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Interspecies Scaling for the Prediction of Drug Clearance in Children

โœ Scribed by Iftekhar Mahmood

Book ID
118203812
Publisher
Springer International Publishing AG
Year
2010
Tongue
English
Weight
178 KB
Volume
49
Category
Article
ISSN
0312-5963

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๐Ÿ“œ SIMILAR VOLUMES

Interspecies scaling of protein drugs: P
Interspecies scaling of protein drugs: Prediction of clearance from animals to humans
โœ Iftekhar Mahmood ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 90 KB

The objective of this study was to evaluate the interspecies scaling for therapeutic protein drugs to predict the systemic clearance in humans from animal data. This study was undertaken to examine whether the rule of exponents of Mahmood and Balian for the prediction of clearance of nonprotein drug