Interrelationship between parathyroid hormone and insulin: Effects on DNA synthesis in UMR-106–01 cells
✍ Scribed by Arnold J. Felsenfeld; Akiko Iida-Klein; Theodore J. Hahn
- Book ID
- 112118996
- Publisher
- American Society for Bone and Mineral Research
- Year
- 2009
- Tongue
- English
- Weight
- 883 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0884-0431
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
We used the osteogenic sarcoma cell line, UMR-106-01, to determine whether the rise in free cytosolic Ca2+ concentration ([Ca"],) and cellular cAMP following PTH stimulation are able to be regulated independently. For this purpose, we compared the effect of a PTH antagonist, stimulation of protein k
The effects of parathyroid hormone (PTH) on 1,4,5-inositol triphosphate (1,4,5-IP 3 ) and intracellular free calcium (Ca i 21 ) in osteoblasts are variable, whereas adenylate cyclase activity is consistently stimulated. Cyclic AMP is considered a mediator in the contractile effects of PTH on osteobl