Interleukin-6 (IL-6) as an autocrine growth factor in oral squamous cell carcinoma In vitro
โ Scribed by Y. Imai; T. Sasaki; K. Akimoto; A. Niwa; T. Fujibayashi
- Book ID
- 117612786
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 94 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0901-5027
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Interleukin (IL)-6 is reported to function as a growth factor for renal and prostatic carcinomas. We conducted the present study to define the role of IL-6 in the growth of normal and neoplastic urothelial cells. Human bladder carcinoma cell lines (253J, RT4 and T24) and primary cultured human uroth
## Background: Recent studies showed that interleukin-6 (il-6) played a role in tumor development. however, available information about the prognostic significance of il-6 and il-6 receptors (il-6r) for oral squamous cell carcinoma (oscc) is limited. ## Methods: Eighty-six patients with oscc were