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Interleukin-6 (IL-6) functions as an in vitro autocrine growth factor in renal cell carcinomas

✍ Scribed by Shunji Miki; Masayuki Iwano; Yoshitsugu Miki; Masahiro Yamamoto; Bo Tang; Kiyoshi Yokokawa; Takao Sonoda; Toshio Hirano; Tadamitsu Kishimoto


Book ID
115922023
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
589 KB
Volume
250
Category
Article
ISSN
0014-5793

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## Abstract Interleukin‐6 (IL‐6) is produced at high levels by renal cell carcinoma cell lines. The molecular mechanisms involved in its possible role as an autocrine growth factor were investigated. IL‐6 and IL‐6 receptor expression was investigated in 8 renal cell carcinoma (RCC) cell lines. The