Interleukin-2 promotes survival and neurite extension of cultured neurons from fetal rat brain
β Scribed by Mokaddez Sarder; Hiroshi Saito; Kazuho Abe
- Book ID
- 115804172
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 357 KB
- Volume
- 625
- Category
- Article
- ISSN
- 0006-8993
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We previously reported that microglial conditioned medium (Mic-CM) has a neurotrophic effect on cultured rat neocortical neurons [Nakajima et al. (1989): Biomed Res 10:411423]. In order to investigate the interaction between microglia and neurons in more detail, we determined the effects of Mic-CM o
## Abstract The expression of adenosine A~1~ receptors was investigated using [^3^H]2βchloroβN^6^ βcyclopentyladenosine (CCPA) in 8βdayβold cultured neurons from fetal rat forebrain grown in serumβfree medium. [^3^H]CCPA bound specifically and with high affinity (Kd = 2.9 nM) to a homogeneous popul