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Interleukin-1β induces cytosolic PLA2in parallel with prostaglandin E2in rheumatoid synovial fibroblasts

✍ Scribed by Keren I. Hulkower; John W. Coffey; Wayne Levin; Celia M. Anderson; Ting Chen; William C. Hope; David R. Bolin; Douglas W. Morgan

Book ID
105420278
Publisher
SP Birkhäuser Verlag Basel
Year
1993
Tongue
English
Weight
283 KB
Volume
39
Category
Article
ISSN
1420-908X

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## Abstract ## Objective Membrane‐associated prostaglandin E synthase (mPGES) is a recently identified terminal enzyme of the arachidonic acid cascade, which converts PGH~2~ to PGE~2~ in rheumatoid arthritis synovial fibroblasts (RASFs). This study was undertaken to investigate factors regulating