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Interleukin-1A (−889) genetic polymorphism increases the risk of multiple system atrophy

✍ Scribed by Onofre Combarros; Jon Infante; Javier Llorca; José Berciano

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
45 KB
Volume
18
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

In a case‐control study using a clinically well‐defined group of 30 multiple system atrophy (MSA) patients and 110 control subjects, homozygosity for interleukin‐1A (IL‐1A) allele 2 (high secretor of proinflammatory cytokine) in the regulatory region (‐889) of the IL‐1A gene was associated with a fivefold increased risk for MSA. © 2003 Movement Disorder Society

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