## Abstract Loss of DNA mismatch repair occurs in a variety of malignancies and is associated with genomeโwide instability of microsatellite repeats, a molecular phenotype referred to as microsatellite instability (MSI). MSI is a consistent feature of colorectal and endometrial tumors from patients
Genetic polymorphism of the plasminogen activator inhibitor-1 is associated with an increased risk of endometrial cancer
โ Scribed by Chung-Kuang Su; Kun-Tu Yeh; Chao-Bin Yeh; Po-Hui Wang; Esther Shih-Chu Ho; Ming-Chih Chou; Kai-Cheng Liu; Shun-Fa Yang; Yu-Chiao Yi
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 81 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
According to present estimations, the unfavorable combination of alleles with low penetrance but high prevalence in the population might account for the major part of hereditary breast cancer risk. Deleted in Malignant Brain Tumors 1 (DMBT1) has been proposed as a tumor suppressor for breast cancer
## Abstract Glutathione Sโtransferases (GSTs) are involved in detoxification of carcinogens, __e.g__., from tobacco smoke. Therefore, polymorphisms in the GST genes have been considered as potential modifiers of individual cancer risk. In a populationโbased caseโcohort study where cases and the sub
## Abstract The genetic polymorphisms in Eโcadherin gene (__CDH1__) may affect invasive/metastatic disease development by altering gene transcriptional activity. In this paper, we investigated the effect of 3โฒโUTR +54C/T polymorphism (rs1801026) in __CDH1__ gene on the risk and progression of sever
The plasminogen activating system is involved in tumor growth and metastasis by degradation of extracellular matrix, and modulation of cell adhesion and migration. Benign and well-differentiated malignant ovarian tumors present as cystic lesions with preserved glandular morphology, whereas poorly di