Interferon-γtherapy in AIDS for mononuclear phagocyte activation
✍ Scribed by Henry W. Murray
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 916 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0921-299X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Among a series of agents, including various interleukins and growth factors, only interferon y (IFNy) and heat-killed Corynebacterium parvurn (CP) organisms were able to elicit, within 24 hr, tumoricidal activity in bone-marrow-derived mononuclear (BMM) phagocytes. In subsequent experiments, the abi
IFN-gamma produced by CD4+ T helper 1 (Th1) cells promotes protection against intracellular pathogens. Antigen activation of Th1 cells is an important mode of IFN-gamma induction, but here we analyze a second, antigen-nonspecific pathway capable of inducing full IFN-gamma transcription. IL-12 or IL-