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Interferon treatment markedly inhibits the development of tumor metastases in the liver and spleen and increases survival time of mice after intravenous inoculation of friend erythroleukemia cells

✍ Scribed by Ion Gresser; Chantal Maury; David Woodrow; Jill Moss; Marcus G. Grütter; Françoise Vicnaux; Filippo Belardelli; Marie-Thérèse Maunoury


Publisher
John Wiley and Sons
Year
1988
Tongue
French
Weight
980 KB
Volume
41
Category
Article
ISSN
0020-7136

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✦ Synopsis


respectively. Solid arrows indicate easily visible foci of tumor cells against background of normal hepatic parenchyma. In (c) the hepatic parenchyma is totally replaced by tumor except for small island of normal liver indicated by an open arrow. Hematoxylin and eosin. X 20.


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Anti-tumor effects of interferon in mice
✍ Ion Gresser; Chantal Maury; Claude Carnaud; Edward De Maever; Marie-Thérése Maun 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 758 KB

DBAl2 mice were injected i.v. with IFN alp-resistant 3C I 8 Friend erythroleukemia cells (FLC) which metastasize to the liver and spleen. IFN d p treatment of FLC-injected mice increased their survival time and these mice developed a resistance to a second challenge with FLC. The efficacy of IFN d p