Interferon treatment markedly inhibits the development of tumor metastases in the liver and spleen and increases survival time of mice after intravenous inoculation of friend erythroleukemia cells
✍ Scribed by Ion Gresser; Chantal Maury; David Woodrow; Jill Moss; Marcus G. Grütter; Françoise Vicnaux; Filippo Belardelli; Marie-Thérèse Maunoury
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- French
- Weight
- 980 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
✦ Synopsis
respectively. Solid arrows indicate easily visible foci of tumor cells against background of normal hepatic parenchyma. In (c) the hepatic parenchyma is totally replaced by tumor except for small island of normal liver indicated by an open arrow. Hematoxylin and eosin. X 20.
📜 SIMILAR VOLUMES
DBAl2 mice were injected i.v. with IFN alp-resistant 3C I 8 Friend erythroleukemia cells (FLC) which metastasize to the liver and spleen. IFN d p treatment of FLC-injected mice increased their survival time and these mice developed a resistance to a second challenge with FLC. The efficacy of IFN d p