𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Interactions of platinum(II)-derivatized triplex-forming oligonucleotides with DNA

✍ Scribed by Campbell, Meghan A; Mason, Tracey McGregor; Miller, Paul S

Book ID
115547642
Publisher
NRC Research Press
Year
2007
Tongue
French
Weight
328 KB
Volume
85
Category
Article
ISSN
0008-4042

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Repair of DNA lesions associated with tr
Repair of DNA lesions associated with triplex-forming oligonucleotides
✍ Joanna Y. Chin; Peter M. Glazer πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 181 KB

## Abstract Triplex‐forming oligonucleotides (TFOs) are gene targeting tools that can bind in the major groove of duplex DNA in a sequence‐specific manner. When bound to DNA, TFOs can inhibit gene expression, can position DNA‐reactive agents to specific locations in the genome, or can induce target

Interaction of DNA with Bis(diiminosucci
Interaction of DNA with Bis(diiminosuccinonitrilo)platinum(II)
✍ Zhi-Gang ZHANG; Yuan-Yuan SUN; Xiao-Ming JIANG πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 102 KB

## Abstract Interaction of DNA with bis(diiminosuccinonitrilo)platinum(II) has been studied by UV‐visible absorbance spectra, fluorescence spectra and viscosity measurements. The UV‐visible absorption spectra of the metal complex exhibit hypochromism with a small blue shift on interaction with DNA.

Synthesis and DNA duplex recognition of
Synthesis and DNA duplex recognition of a triplex-forming oligonucleotide with an ureido-substituted 4-phenylimidazole nucleoside
✍ Falk Wachowius; Michael Rettig; Gottfried Palm; Klaus Weisz πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 French βš– 211 KB

A 4-(3-n-butylureidophenyl)imidazole nucleoside was successfully incorporated into a triplex-forming oligonucleotide (TFO). Binding affinity and base pair selectivity of the TFO containing this non-natural nucleoside were studied with various duplex targets containing all four possible Watson-Crick