๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Modulation of Psoralen DNA Crosslinking Kinetics Associated with a Triplex-forming Oligonucleotide

โœ Scribed by Dennis H. Oh; Vincent Suzara; Rajagopal Krishnan

Book ID
111413136
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
320 KB
Volume
84
Category
Article
ISSN
0031-8655

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Repair of DNA lesions associated with tr
Repair of DNA lesions associated with triplex-forming oligonucleotides
โœ Joanna Y. Chin; Peter M. Glazer ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 181 KB

## Abstract Triplexโ€forming oligonucleotides (TFOs) are gene targeting tools that can bind in the major groove of duplex DNA in a sequenceโ€specific manner. When bound to DNA, TFOs can inhibit gene expression, can position DNAโ€reactive agents to specific locations in the genome, or can induce target

Synthesis and DNA duplex recognition of
Synthesis and DNA duplex recognition of a triplex-forming oligonucleotide with an ureido-substituted 4-phenylimidazole nucleoside
โœ Falk Wachowius; Michael Rettig; Gottfried Palm; Klaus Weisz ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 211 KB

A 4-(3-n-butylureidophenyl)imidazole nucleoside was successfully incorporated into a triplex-forming oligonucleotide (TFO). Binding affinity and base pair selectivity of the TFO containing this non-natural nucleoside were studied with various duplex targets containing all four possible Watson-Crick