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Interactions between programmed death 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) gene polymorphisms in type 1 diabetes

✍ Scribed by Scherezade Momin; Sylvia Flores; Bárbara Angel B; Ethel Codner D; Elena Carrasco P; Francisco Perez-Bravo


Book ID
116406432
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
204 KB
Volume
83
Category
Article
ISSN
0168-8227

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Genetic susceptibility to type 1 autoimmune hepatitis is indicated by a preponderance of female subjects and strong associations with human leukocyte antigens (HLA) DRB1\*0301 and DRB1\*0401. The gene encoding cytotoxic T-lymphocyte antigen-4 (CTLA-4) on chromosome 2q33 may also influence autoimmuni