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Association of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with type 1 autoimmune hepatitis in Japanese

✍ Scribed by Takeji Umemura; Masao Ota; Kaname Yoshizawa; Yoshihiko Katsuyama; Tetsuya Ichijo; Eiji Tanaka; Kendo Kiyosawa


Book ID
118087961
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
81 KB
Volume
38
Category
Article
ISSN
1386-6346

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Cytotoxic T lymphocyte antigen-4 (CTLA-4
✍ Kosh Agarwal; Albert J. Czaja; David E. Jones; Peter T. Donaldson πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 78 KB

Genetic susceptibility to type 1 autoimmune hepatitis is indicated by a preponderance of female subjects and strong associations with human leukocyte antigens (HLA) DRB1\*0301 and DRB1\*0401. The gene encoding cytotoxic T-lymphocyte antigen-4 (CTLA-4) on chromosome 2q33 may also influence autoimmuni