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Cytotoxic T lymphocyte antigen–4 gene polymorphisms do not confer susceptibility to autoimmune hepatitis types 1 and 2 in Brazil

✍ Scribed by Paulo L Bittencourt; Selma A Palácios; Eduardo L.R Cançado; Gilda Porta; Flair J Carrilho; Antonio A Laudanna; Jorge Kalil; Anna C Goldberg


Book ID
119394131
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
79 KB
Volume
98
Category
Article
ISSN
0002-9270

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Cytotoxic T lymphocyte antigen-4 (CTLA-4
✍ Kosh Agarwal; Albert J. Czaja; David E. Jones; Peter T. Donaldson 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 78 KB

Genetic susceptibility to type 1 autoimmune hepatitis is indicated by a preponderance of female subjects and strong associations with human leukocyte antigens (HLA) DRB1\*0301 and DRB1\*0401. The gene encoding cytotoxic T-lymphocyte antigen-4 (CTLA-4) on chromosome 2q33 may also influence autoimmuni