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Interaction of strain and interleukin-1 in articular cartilage: effects on proteoglycan synthesis in chondrocytes

✍ Scribed by Robert J. Gassner; Michael J. Buckley; Rebecca K. Studer; Chris H. Evans; Sudha Agarwal


Book ID
114422214
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
151 KB
Volume
29
Category
Article
ISSN
0901-5027

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Objective. To study the effect of bone morphogenetic protein 2 (BMP-2) on articular cartilage proteoglycan (PG) synthesis in vivo and to investigate whether BMP-2 is able to counteract the effects of interleukin-1 (IL-1) on articular cartilage PG synthesis and content. Methods. BMP-2 alone or in co