Interaction of ribonucleosides with copper(II) acetate

✍ Scribed by Stephen J. Kirchner; Quintus Fernando; Milos Chvapil

• Publisher: Elsevier Science
• Year: 1977
• Tongue: English
• Weight: 203 KB
• Volume: 25
• Category: Article
• ISSN: 0020-1693
• DOI: 10.1016/s0020-1693(00)95637-8

✦ Synopsis

An argument commonly

used to interpret the specificity of interaction between molecules is stereoselective fit. Bond distances, bond angles, and configurations determined from X-ray structures in the solid state are quite often used to explain the seemingly selective behavior of molecules or ions in solution. Recently, the rationale of stereoselectivity was used to explain the interaction of dimeric copper (11) acetate hydrate, (CU~(CH,COO)~*~H~O), with the hydroxy groups of the sugar moieties in ribonucleosides and deoxyribonucleosides in the solvent, dimethylsulfoxide [1, 21. In the proposed reaction scheme, one of the acetate groups in the copper(R) acetate is displaced by the ribose unit in the ribonucleoside.