Interaction of naproxen with α-, β-, and γ-hydroxypropyl cyclodextrins in solution and in the solid state
✍ Scribed by F. Melani; G. P. Bettinetti; P. Mura; A. Manderioli
- Publisher
- Springer Netherlands
- Year
- 1995
- Tongue
- English
- Weight
- 760 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0923-0750
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The interaction between spironolactone (Sp) and hydroxypropyl-b-cyclodextrin (HPbCD) has been investigated in aqueous solution and in the solid state. Phase solubility studies indicate that the complex is formed with possible stoichiometry of 1:1 and association constant of 9806 M À1 . Differential
Inclusion complexation between celecoxib, a specific cyclooxygenase II inhibitor, and beta-cyclodextrin (b-CD) was studied in solution and solid state. Drug cyclodextrin complexes were prepared by spray drying while physical mixtures were obtained by simple blending. Inclusion complexes were charact
Hydroxypropyl-beta-cyclodextrin (HPBCD) was investigated as a possible solubilizer for a series of poorly water-soluble antimalarial drugs. The solubilities of artemisinin, artether, dihydroartemisinin, and 10-deoxoartemisinin in HPBCD solutions were studied. The phase-solubility profile of these dr