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Interaction of homo-aza-steroidal ester of [p-[bis-(2-chloroethyl) amino]phenyl]acetic acid (ASE) with DNA of Ehrlich ascites tumor cells

โœ Scribed by A. Papageorgiou; I.G. Ivanov; G.G. Markov; S.I. Koliais; L. Boutis; P. Catsoulakos


Book ID
115914299
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
492 KB
Volume
153
Category
Article
ISSN
0014-5793

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Chromosome damage and SCE induced by the
โœ Athanasiou, Kyriacos ;Demopoulos, Nicos A. ;Catsoulacos, Panayiotis ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Wiley (John Wiley & Sons) โš– 322 KB

The cytogenetic effects of homo-aza-steroidal ester (ASE) on Chinese hamster ovary (CHO) cells in vitro are reported. It was found that treatment of cells with a dose as low as 0.025 pglml of ASE causes a significant number of abnormal metaphases containing mostly chromatid-type aberrations. Similar