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Interaction of brevetoxin A with a new receptor site on the sodium channel

✍ Scribed by William A. Catterall; Marjorie Gainer

Book ID
119006180
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
527 KB
Volume
23
Category
Article
ISSN
0041-0101

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## Abstract Anthopleurin A, a polypeptide toxin from the Pacific sea anemone Anthopleura xanthogrammica, enhances persistent activation of voltage‐senstive sodium channels by the alkaloid toxins veratridine and batrachotoxin with K~0.5~ = 20 nM. This effect is inhibited by depolarization. There is