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Interaction of anthracycline antibiotics with biopolymers: 7. Equilibrium binding studies on the interaction of iremycin and DNA

✍ Scribed by A. Walter; H. Schültz; E. Stutter

Book ID
119069906
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
437 KB
Volume
5
Category
Article
ISSN
0141-8130

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Interaction of anthracycline antibiotics
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✍ Dr. E. Stutter; Axel Walter; Werner F. Fleck 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 805 KB

The binding of the anthracyclines beta-rhodomycin-I and beta-rhodomycin-II to calf thymus DNA was investigated by both equilibrium and kinetic methods taking into account ligand dimerization (ionic strength I = 0.2 M, pH 6.0). The analysis was based upon a cooperative single-step binding mechanism w