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Interaction between valproic acid and aspirin in epileptic children: Serum protein binding and metabolic effects

✍ Scribed by Orr, James M; Abbott, Frank S; Farrell, Kevin; Ferguson, Sheila; Sheppard, Ian; Godolphin, William


Book ID
109843237
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
538 KB
Volume
31
Category
Article
ISSN
0009-9236

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Plasma protein binding interaction betwe
✍ C. T. Viswanathan; R. H. Levy πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 308 KB

The effects of three levels of salicylic acid on the steady-state plasma concentrations of free and total valproic acid were examined in catheterized rhesus monkeys. Valproate was infused intravenously for a total of 41 hr, and salicylate was added after the first 8 hr. The three salicylate infusion