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Integrin αvβ3-mediated transcriptional regulation of TIMP-1 in a human ovarian cancer cell line

✍ Scribed by Dong Seok Kim; Ok-Hee Jeon; Hee Doo Lee; Kyung Ho Yoo; Doo-Sik Kim


Book ID
116297568
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
406 KB
Volume
377
Category
Article
ISSN
0006-291X

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## Abstract We previously showed that integrin αvβ3 overexpression and engagement by its ligand vitronectin increased adhesion, motility, and proliferation of human ovarian cancer cells. In search of differentially regulated genes involved in these tumor biological events, we previously identified