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Tumor-Selective Response to Antibody-Mediated Targeting of αvβ3 Integrin in Ovarian Cancer

✍ Scribed by Landen, Charles N.; Kim, Tae-Jin; Lin, Yvonne G.; Merritt, William M.; Kamat, Aparna A.; Han, Liz Y.; Spannuth, Whitney A.; Nick, Alpa M.; Jennnings, Nicholas B.; Kinch, Michael S.; Tice, David; Sood, Anil K.


Book ID
122303274
Publisher
Neoplasia Press
Year
2008
Tongue
English
Weight
403 KB
Volume
10
Category
Article
ISSN
1522-8002

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## Abstract We previously showed that integrin αvβ3 overexpression and engagement by its ligand vitronectin increased adhesion, motility, and proliferation of human ovarian cancer cells. In search of differentially regulated genes involved in these tumor biological events, we previously identified