Integrin α5β1 Ligands: Biological Evaluation and Conformational Analysis

Probing Integrin Selectivity: Rational D

Probing Integrin Selectivity: Rational Design of Highly Active and Selective Ligands for the α5β1 and αvβ3 Integrin Receptor

✍ Dominik Heckmann; Axel Meyer; Luciana Marinelli; Grit Zahn; Roland Stragies; Hor 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 323 KB 👁 1 views

Synthesis and Biological Evaluation of H

Synthesis and Biological Evaluation of Highly Active Nonpeptidic α- vs. β-3 Integrin Antagonists

✍ Georgette Thumshirn; Gabor A. G. Sulyok; Dirk Weber; Simon L. Goodman; Matthias 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 62 KB

Design, Synthesis, and Biological Evalua

Design, Synthesis, and Biological Evaluation of α4β1 Integrin Antagonists Based on β-D-Mannose as Rigid Scaffold

✍ Jürgen Boer; Dirk Gottschling; Anja Schuster; Bernhard Holzmann; Horst Kessler 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

The tuning of protein ± protein interactions by small nonpeptidic molecules remains one of the great challenges in medicinal chemistry. Although already proposed in 1980 by Farmer, [1] only a few successful examples on the synthesis of peptidomimetics based on rigid scaffolds such as cyclohexane and

Design, Synthesis, and Biological Evalua

Design, Synthesis, and Biological Evaluation of α4β1 Integrin Antagonists Based on β-D-Mannose as Rigid Scaffold

✍ Jürgen Boer; Dirk Gottschling; Anja Schuster; Bernhard Holzmann; Horst Kessler 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

The tuning of protein ± protein interactions by small nonpeptidic molecules remains one of the great challenges in medicinal chemistry. Although already proposed in 1980 by Farmer, [1] only a few successful examples on the synthesis of peptidomimetics based on rigid scaffolds such as cyclohexane and

ChemInform Abstract: Discovery and Evalu

ChemInform Abstract: Discovery and Evaluation of Potent, Cysteine-Based α4β1 Integrin Antagonists.

✍ Sarah C. Archibald; John C. Head; Janeen M. Linsley; John R. Porter; Martyn K. R 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB

ChemInform Abstract: Discovery and Evalu

ChemInform Abstract: Discovery and Evaluation of Potent, Tyrosine-Based α4β1 Integrin Antagonists.

✍ Sarah C. Archibald; John C. Head; Neil Gozzard; David W. Howat; Ted A. H. Parton 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v