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Integrin-Mediated Signalling of Gelatinase B Secretion in Colon Cancer Cells

✍ Scribed by J. Niu; X. Gu; J. Turton; C. Meldrum; E.W. Howard; M. Agrez


Book ID
115582522
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
626 KB
Volume
249
Category
Article
ISSN
0006-291X

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The αvβ6 integrin induces gelatinase B s
✍ Michael Agrez; Xinhua Gu; Jacqueline Turton; Cliff Meldrum; Jun Niu; Toni Antali 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 198 KB

In human cancers, the co-operative role between celladhesion receptors and proteases capable of degrading matrix barriers remains poorly understood. We have previously reported that the epithelium-restricted integrin ␣v␤6 becomes highly expressed in colon cancer compared with normal mucosa and that