Integration of hepatitis virus DNA near c-myc in woodchuck hepatocellular carcinoma
✍ Scribed by Hsu, Tsuey-ying ;Fourel, Geneviéve ;Etiemble, Jeanne ;Tiollais, Pierre ;Buendia, Marie-Annick
- Publisher
- Springer-Verlag
- Year
- 1990
- Tongue
- English
- Weight
- 937 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0435-1339
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The chromosomal sites of woodchuck hepatitis virus (WHV) DNA integration were identified in a woodchuck hepatocellular carcinoma-derived cell line (WH257GE 10) by the in situ hybridization technique using 'H-labelled WHV whole genome (WHV 2) as a probe. The C-banded chromosome spreads from WH257GE 1
The leading cause of human hepatocellular carcino-been observed in hepatocellular carcinomas (HCCs), mas (HCCs) is hepatitis B virus (HBV) infection. Woodmaking the prognosis for patients with HCC very poor. 6 chucks infected with a closely related hepadnavirus, HCC is one of the most common cancers
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