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Insulin-like Growth Factor I Receptor Antagonism Augments Response to Chemoradiation Therapy in Colon Cancer Cells

โœ Scribed by Elise S. Perer; Atul K. Madan; Autumn Shurin; Ellen Zakris; Keith Romeguera; Ying Pang; Derrick J. Beech

Book ID
115636176
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
140 KB
Volume
94
Category
Article
ISSN
0022-4804

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โœ Yan-Shi Guo; Gui-Fang Jin; Clifford W. Houston; James C. Thompson; Courtney M. T ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 259 KB ๐Ÿ‘ 1 views

Insulin-like growth factor-I (IGF-I) is known as a potent mitogen for a variety of cell types, including colon cancer cell lines. The objective of this study was to determine the effect of IGF-I on cell death induced by cytotoxic agents actinomycin D (Act-D), lovastatin (LOV), and doxorubicin (DOX)