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Insulin-like growth factor 2 and its receptors (IGF 1R and IGF 2R/mannose 6-phosphate) in endometrial adenocarcinoma

✍ Scribed by Jasminka Pavelić; Branko Radaković; Krešimir Pavelić

Book ID: 113961022
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 181 KB
Volume: 105
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2007.02.012

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## Background and Objectives: We have previously shown that insulin-like growth factor (IGF)-responsive murine sarcomas demonstrate inhibition of local and metastatic disease growth when implanted in an IGF-deficient host animal. In this experiment, we tested whether IGF receptor (IGF-R) and ligan