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Insulin-induced NADPH oxidase activation promotes proliferation and matrix metalloproteinase activation in monocytes/macrophages

✍ Scribed by Gorka San José; Julen Bidegain; Pablo A. Robador; Javier Díez; Ana Fortuño; Guillermo Zalba


Book ID
113630807
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
657 KB
Volume
46
Category
Article
ISSN
0891-5849

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## Objective: To determine the effects of peroxisome proliferator-activated receptor gamma (ppargamma) agonists on interleukin-1 (il-1) induction of nitric oxide (no) and matrix metalloproteinase 13 (mmp-13) in human chondrocytes. ## Methods: Ppargamma expression and synthesis in human chondrocyt