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Transcription factor decoys for activator protein-1 (AP-1) inhibit oxidative stress-induced proliferation and matrix metalloproteinases in rat cardiac fibroblasts

✍ Scribed by Shuanglun Xie; Ruqiong Nie; Jingfeng Wang; Fei Li; Woliang Yuan

Book ID: 119383264
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 377 KB
Volume: 153
Category: Article
ISSN: 1931-5244
DOI: 10.1016/j.trsl.2008.11.004

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## Abstract The effect of Cadmium (Cd) on the expression of c‐Jun __N__‐terminal kinase (JNK), __c‐jun__, and activator protein‐1 (AP‐1) has been investigated. We previously reported that Cd causes cell damage as indicated by increases in the cytotoxic parameters, lactate dehydrogenase and lipid pe