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Peroxisome proliferator activated receptor-γ ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells

✍ Scribed by Jiajun Liu; Huiling Lu; Renwei Huang; Dongjun Lin; Xiangyuan Wu; Qu Lin; Xinyao Wu; Jing Zheng; Xianglin Pan; Jun Peng; Yuqin Song; Maohong Zhang; Ming Hou; Feng Chen

Publisher
Springer
Year
2005
Tongue
English
Weight
522 KB
Volume
56
Category
Article
ISSN
0344-5704

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Peroxisome proliferator–activated receptor γ activators inhibit interleukin-1β–induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes
✍ Hassan Fahmi; John A. Di Battista; Jean-Pierre Pelletier; François Mineau; Pierr 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 759 KB

## Objective: To determine the effects of peroxisome proliferator-activated receptor gamma (ppargamma) agonists on interleukin-1 (il-1) induction of nitric oxide (no) and matrix metalloproteinase 13 (mmp-13) in human chondrocytes. ## Methods: Ppargamma expression and synthesis in human chondrocyt