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Instability of short tandem repeats (microsatellites) in human cancers

✍ Scribed by Wooster, R.; Cleton-Jansen, A.-M.; Collins, N.; Mangion, J.; Cornelis, R.S.; Cooper, C.S.; Gusterson, B.A.; Ponder, B.A.J.; von Deimling, A.; Wiestler, O.D.


Book ID
109915142
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
585 KB
Volume
6
Category
Article
ISSN
1061-4036

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Human breast-cancer specimens from 100 patients were analyzed for microsatellite instability (referred to as replication error; RER) at I 2 genomic loci on 7 chromosomes, and results were correlated with clinicopathologic characteristics. In 42 of I00 breast-cancer patients, we investigated whether