Tetra-and pentanucleotide short tandem repeat instability in gastric cancer
✍ Scribed by Dr. Filipe Silva; Leonor Gusmão; Cíntia Alves; Raquel Seruca; Leonor David; António Amorim
- Book ID
- 102181543
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 326 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0173-0835
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We have previously cloned and identified a novel esophageal cancer related gene 2 (ECRG2; GenBank Accession Number AF268198), which is down-regulated in esophageal squamous cell carcinoma (ESCC) and involved in the induction of the apoptosis in esophageal cancer cell lines. In the present study, we
## Abstract We evaluated DNA polymorphisms in the __thymidylate synthase (TS__) and 5,10‐__methylene‐tetrahydrofolate reductase (MTHFR__) genes for an association with response and survival in locally advanced gastric cancer treated with 5‐FU based preoperative chemotherapy (CTx). DNA of 238 patien