Instability and chromatin structure of expanded trinucleotide repeats
โ Scribed by Vincent Dion; John H. Wilson
- Book ID
- 113933031
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 320 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0168-9525
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Recently, unstable trinucleotide repeats have been shown to be the etiologic factor in seven neuropsychiatric diseases, and they may play a similar role in other genetic disorders which exhibit genetic anticipation. We have tested one polymerase chain reaction (PCR)-based and two hybridizationbased